Symbol
Name
ID

Ighg1
immunoglobulin heavy constant gamma 1 (G1m marker)
MGI:96446

Phenotype annotations related to immune system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

immune system phenotype

abnormal class switch recombination

abnormal plasma cell differentiation

increased germinal center B cell number

absent memory B cells

increased plasma cell number

abnormal B cell physiology

increased IgE level

decreased IgG1 level

increased IgG1 level

increased IgG2a level

increased IgG2b level

decreased IgG2c level

increased susceptibility to type I hypersensitivity reaction

enhanced humoral immune response

increased autoantibody level

increased anti-nuclear antigen antibody level

increased anti-double stranded DNA antibody level

Availability

Mouse Genotype

Ighg1^em1Wliu/Ighg1^em1Wliu

Ighg1^tm1.1Ksho/Ighg1^tm1.1Ksho

Ighg1^tm1.1Pyu/Ighg1^tm1.1Pyu

Ighg1^tm1Ksho/Ighg1^tm1Ksho

Ighg1^tm4Cgn/Ighg1^tm4Cgn

Ighg1^tm1.1Ksho/Ighg1⁺

Ighg1^tm1.1Pyu/Ighg1⁺

Ighg1^tm1Ksho/Ighg1⁺

Ighg1^tm2Cgn/Ighg1⁺

Ighg1^tm3Cgn/Ighg1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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